schrodinger.application.bioluminate.tcr.annotate module

schrodinger.application.bioluminate.tcr.annotate.get_tcr_bounds(scheme)

schrodinger.application.bioluminate.tcr.annotate.get_scheme_region_prop(scheme)

schrodinger.application.bioluminate.tcr.annotate.get_anarci_alignment_best_match(chain, scheme=AntibodyCDRScheme.IMGT)

schrodinger.application.bioluminate.tcr.annotate.get_tcr_type_name(chain)

schrodinger.application.bioluminate.tcr.annotate.filter_structure_chains(ct, chain_names=None)

schrodinger.application.bioluminate.tcr.annotate.get_tcr_variable_domain_details(chain, scheme=AntibodyCDRScheme.IMGT)

schrodinger.application.bioluminate.tcr.annotate.renumber_tcr_structure(ct, chain_names=None, scheme=AntibodyCDRScheme.IMGT)

This function takes as input a structure with zero or more TCR domains and uses ANARCI to renumber all residues of each user-specified chain according their TCR-defined IMGT or AHo schemes. Variable domain numbers are directly computed via ANARCI, and constant domain residues are numbered sequentially.

schrodinger.application.bioluminate.tcr.annotate.annotate_tcr_regions(ct, chain_names=None, scheme=AntibodyCDRScheme.IMGT)

This function takes as input a structure with zero or more TCR domains, and modifies the structure such that all TCR domains in the structure have their CA atoms annotated with the appropriate TCR chain, framework, or loop region property.